About American Cleanroom Systems

American Cleanroom Systems® is a specialized manufacturer and installer of modular cleanroom solutions with over 45 years of industry experience since 1976. The company designs, manufactures, and installs cleanrooms across a broad spectrum of classifications—from ISO 5 to ISO 8 and Class 100 to Class 100,000—serving pharmaceutical, medical device, food processing, electronics, and industrial applications. Their expertise encompasses complete system design, custom engineering, air flow management, wall systems, flooring, ceilings, and monitoring equipment, positioning them as comprehensive cleanroom solution providers.

The firm maintains an impressive client roster including major corporations and government institutions such as Apple, Intel, Johnson & Johnson, Medtronic, NASA, and various National Laboratories. This customer base reflects their capability to meet stringent regulatory requirements, particularly in FDA validation and CGMP or GMP cleanroom environments requiring advanced quality assurance protocols. American Cleanroom Systems distinguishes itself through rapid turnaround—offering quotes in 48 hours—combined with modular construction that enables flexible design, fast assembly, and straightforward modification.

Why Choose American Cleanroom Systems

  • Made in USA manufacturing
  • Fast assembly and installation
  • Flexible modular design
  • Expert engineering staff
  • Decades of experience since 1976

Notable Clients

AppleAllerganBrookhaven National LaboratoryIntelJohnson & JohnsonLockheedMedtronicNISTRegeneronUS NavyBoeingGoogleIBMNASARaytheon

Key Capabilities

Turnkey Solutions

Complete start-to-finish project delivery

Design-Build Services

Integrated design and construction

Installation Services

Professional on-site installation

Consulting Services

Expert guidance and planning

Services

Manufacturer
Contractor
Designer
Installer
Modular Cleanrooms
Softwall Cleanrooms

Project Types

ModularSoftwallHardwallCustom

Validation Services

CertificationProduct Testing

Technical Specifications

ISO Classifications Supported

ISO 1
ISO 5
ISO 6
ISO 7
ISO 8

Cleanroom Types

HardwallSoftwallModularHybrid

Wall Materials

FRPVinylAluminumMelamine

Flooring Options

ESD vinylEpoxyVinyl with integral coveRaised floor

Filtration Systems

HEPAULPA

Environmental Controls

Temperature Control Precise temperature management
Humidity Control Controlled humidity levels

Industries Served

CleanroomsCleanroom Buildings & EnclosuresCleanroom EnclosuresCleanroom BuildingsPharmaceuticalMedical DeviceFood ProcessingElectronicsAerospaceResearch & DevelopmentIndustrial ManufacturingFood & BeverageCompounding PharmaciesResearch

Certifications & Compliance

Certifications listed are as reported by the supplier and have not been independently verified by Cleanroom.com.

Certifications

ISO 5
ISO 6
ISO 7
ISO 8
GMP
CGMP
FDA
USP 797
USP 800
NSF
ISO 14644
ISO 13485
FEDERAL STANDARD 209E

Contact Information

Phone Numbers

Main: 949-589-5656

Email Addresses

Locations

Headquarters:
23221 Arroyo Vista, Rancho Santa Margarita, California 92688

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